In a case of postrenal azotemia due to cervical cancer, which anatomic location is most likely the source of obstruction?

• A. Colon
• B. Kidney
• C. Ureter
• D. Uterine cervix

Answer: (D)

In postrenal azotemia, the underlying issue results from obstruction in the urinary tract that hinders the flow of urine. In the context of cervical cancer, the most likely source of obstruction is the uterine cervix itself. Cervical cancer can grow locally and invade surrounding structures, leading to compression or obstruction of the ureters. When the ureters are obstructed, it can result in expanded kidneys (hydronephrosis) and impaired renal function, which manifests as azotemia.

The uterine cervix is directly involved in this scenario as it is the site of the primary malignancy. As the tumor progresses, it can exert pressure on the surrounding anatomical structures, including the ureters, leading to obstructive uropathy. Thus, the cervical cancer's growth at the level of the uterine cervix would be the most direct cause of the associated urinary obstruction in this patient, making it the correct source of obstruction in postrenal azotemia due to this condition.